In Silico Clinical Trials

When a biomolecule is designed to target a pathological condition there will be many side effects associated with it. Hugely complex nature of human diseases, the significant differences between individuals, and the inevitable variability in how a treatment is administered, makes it not unusual for a product to perform exceptionally well in tightly controlled laboratory studies. There is also a high risk associated with the subjects under trial. In order to reduce this risk in silico testing methods are adopted.

In silico clinical trials is basically the use of individualized computer simulation in the development or regulatory evaluation of a medicinal product, medical device, or medical intervention. This is considered to be a promising testing method in clinical trials due to the ethical issues associated with the human and animal testing.

  • In-silico pre-clinical trials for implantable materials
  • In silico study of drug behavior

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